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In addition, in vitro models of primary human adipose stem cells, researchers detected intracellular fat content and quantitative expression of early and mature adipocyte markers (PPAR, FABP4, and HSL), demonstrating that glucagon can significantly reduce adipocyte differentiation, inhibit adipocyte proliferation and adipogenesis

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[PubMed: 24099027] (Review of HDS induced liver injury including regulatory problems, difficulties in diagnosis and assessing causality

Novo is also moving another GLP-1/amylin drug, zenagamtide (which used to be called amycretin), into Phase III testing